Examining the mechanisms of anxiety regulation using a novel, sham-controlled, fMRI-guided rTMS protocol and a translational laboratory model of anxiety

Brief description of study

This research study is being conducted to learn more about how brain stimulation [transcranial magnetic stimulation (TMS)] affects fear and anxiety through memory and attention tasks. We hope to better understand brain processes related to fear and anxiety. If you agree to join the study, you will be asked to complete the following research procedures: memory tests, NPU tasks, MRI scans, and TMS. Sometimes the TMS will be real and sometimes it will be fake (placebo/sham). Neither you nor the TMS operator will know which type of TMS you are being given. Your participation will last for 12 days over the course of 5 weeks. The most common risks of participation are discomfort during clinical interviews, MRI scans, electric shocks, and TMS. For the electric shock, we will find the level of intensity that is unpleasant, but tolerable.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
anxiety
Age: Between 18 Years - 60 Years
Gender: All

Updated on 09 Mar 2024. Study ID: 833320

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