Chronic insomnia and CSF markers of dementia
For the first visit, you would answer some questions about your sleep, thoughts and feelings. You would be asked to wear an activity monitoring device called an actiwatch for one week at home and complete a sleep diary throughout the week. You would also be asked to wear a portable sleep monitor device for one night.
The lumbar puncture is generally considered a safe procedure, and involves placing a thin needle below where the spinal cord is so there’s no risk of damage. Lidocaine is used to numb the area so most patients experience some pressure during the procedure but no pain. A small number of patients experience a temporary headache afterwards.
Subjects with insomnia will have the option of participating in phase 2, where they would receive Cognitive-Behavioral Therapy for Insomnia (CBT-I) for 6-8 weeks and then repeat the hospital visit for a second lumbar puncture:
- Study Identifier: 829221
Contact the research team to learn more about this study.
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