REDUCE Study: For patients with Elevated Left Atrial Pressure with Heart Failure

REDUCE Study: For patients with Elevated Left Atrial Pressure with Heart Failure

Brief description of study

This study is assessing the safety and tolerability of an interatrial septal device implanted for those who have a dilated left atrium or some degree of diastolic dysfunction. This is often known as preserved ejection fraction heart failure. This study is blinded over the course of 2 years, and there is a crossover period at the end for those who still meet criteria and who were in the control group.

Detailed description of study

Clinic visits involve physical exam, blood work, EKG, 6 minute walk test, and questionnaires. 

Visits:
Screening visit in clinic
Randomization and procedure date (this would include a right heart catheterization and exercise bike, to assess hemodynamics at peak exercise)

Follow up clinic visits:
1 month 
3 month
6 month
12 month
24 month
every year after that

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Cardiology,HFPEF,research,atrial fibrillation,diastolic dysfunction,dyspnea,shortness of breath,heart failure
  • Age: Between 40 Years - 100 Years
  • Gender: All


Updated on 01 Nov 2022. Study ID: 827489

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center