Genome Research in African American Scleroderma

Genome Research in African American Scleroderma

Brief description of study

frican Americans who have systemic sclerosis (scleroderma) and are currently patients at Penn Medicine are eligible for this study. African Americans seem to have a higher risk of developing scleroderma than other populations. This research is being done to determine how variations in genes may explain this different risk. There is 1 study visit that includes a blood draw. This can be combined with an already scheduled clinic visit. We will collect blood samples to obtain DNA and serum and collect clinical data. We are not studying new treatments for scleroderma. As part this study, genetic information will be collected and sent to the National Institutes of Health (NIH) Genome-Wide Association Study (GWAS) repository. Personal information that could identify a patient will NOT be sent to the NIH. Information from African American patients will be compared with African Americans and West Africans who do not have scleroderma and who are also in the study.

Detailed description of study

There is 1 study visit that includes a blood draw. This can be combined with an already scheduled clinic visit. We will collect blood samples to obtain DNA and serum and collect clinical data. We are not studying new treatments for scleroderma. As part this study, genetic information will be collected and sent to the National Institutes of Health (NIH) Genome-Wide Association Study (GWAS) repository. Personal information that could identify a patient will NOT be sent to the NIH. There is no cost to take part nor any payment for participating.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Scleroderma,systemic sclerosis,African-American
  • Age: Between 18 Years - 90 Years
  • Gender: All


Updated on 06 Jul 2023. Study ID: 820266

Interested in the study

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