Treatments Against Rheumatoid Arthritis and Effect on FDG PET-CT: TARGET

Site Image

Study Overview

This research study is being done to test the effect, safety, and tolerability of the experimental drug JBT-101 in subjects with systemic lupus erythematosus (SLE). We want to know if JBT-101 stops inflammation and how well JBT-101 is tolerated. The study will evaluate whether JBT-101 will decrease the pain associated with active arthritis or tendonitis. JBT-01 is not approved by the U.S. Food and Drug Administration (FDA) and can only be used in research studies. There are 6 study visits over 5 months. This study will compare JBT-101 to placebo which is a pill that doesn't have any drug in it. It is also double-blind means that both subjects and the researchers do not know whether a subject receives the study drug or a placebo. In case of an emergency, however, the study doctor can get this information.

Study Description

Patients must have a diagnosis of Systemic Lupus Erythematosus and active joint arthritis in at least 2 joints. Patients are not eligible if they have aggressive and advancing organ disease, HIV or Hepatitis C, are taking daily doses of prednisone over 10mg for more than 30 days, use opiates chronically, or use recreational drugs.

Additional Information:

Participants will receive $50 per study visit ($350 total) and free RA medication (excluding methotrexate) for the duration of the trial. 

  • Study Identifier: 828509

Recruitment Status


Contact the research team to learn more about this study.

Fields marked with asterisk (*) are required

Please verify that you are not a bot.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.

Volunteer Sign up

Volunteer Sign-up

Participate in medical studies to develop new diagnostic and clinical treatments and improve current standards of care.

Sign Up Now!

If you need assistance finding a non-cancer study or if you have any questions, please email