Low-Dose Naltrexone to Improve Physical Health in Patients with Vasculitis (LoDoNaVasc)

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Study Overview

The purpose of this study is to see whether a drug called naltrexone improves health-related quality of life in patients with vasculitis. Naltrexone is a prescription drug approved for a different reason at a higher dose than the dose used in this study. However, “low dose naltrexone” is widely used, without insurance coverage, for a wide range of conditions associated with pain or fatigue. We hope to learn more about the impact of low dose naltrexone on the symptoms caused by vasculitis.

Study Description

Patients must have a diagnosis of vasculitis and significantly low quality of life caused by some combination of pain, fatigue, poor physical health, and difficulty carrying out activities. Medication used to treat vasculitis, pain, and fatigue must be stable for 12 weeks before a patient can enroll in the study.

  • Study Identifier: 829492

Recruitment Status

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