Neural Basis Of Eating Behavior In Abstinent Smokers

Brief Description Of Study

The purpose of this study is to evaluate brain responses to food in smokers during a short smoking abstinence period compared to smoking as usual. Non-smokers will also be recruited in this study to examine brain responses.

Detailed Study Description

Smoking participants will be asked to complete an Intake Visit to determine eligibility, a Baseline Visit to collect measures and two 4-day study periods: one while smoking as usual and the other while not smoking (even a single puff) for the entire period. During these periods you will be asked to complete phone calls to discuss your eating and drinking activity with a trained staff member. You would be asked to come to our Center on 4 consecutive days of each period for a monitoring visit; on the 4th visit of each period you would complete an MRI scan session. The MRI scans will last approximately 1 hour and take place in a standard, closed MRI scanner where your brain activity will be measured using a technique called functional magnetic resonance imaging (fMRI). The entire study will take approximately 6-8 weeks for you to complete. In addition to smokers, we are also recruiting non-smokers to serve as a control group for this study. As a member of the control group you will be asked to complete an Intake Visit to determine study eligibility, a Baseline Visit to collect measures, Dietary Recall phone assessments and one fMRI Scanning Visit during which you will complete a 1hr MRI scan. The entire study will take approximately 2-3 weeks for you to complete. Both smoking and control participants will be compensated for their time and for travel.

Additional Information About The Study

Please go to www.smokingfoodstudy.com or call 215-746-6828 to see if you are eligible for this research study.

ClinicalTrials.gov Identifier: NCT03438188


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