Comparing Effectiveness of Aripiprazole Augmentation, rTMS Augmentation, and Switching to Venlafaxine XR in Treatment Resistant Depression (ASCERTAIN-TRD)

Comparing Effectiveness of Aripiprazole Augmentation, rTMS Augmentation, and Switching to Venlafaxine XR in Treatment Resistant Depression (ASCERTAIN-TRD)

Brief description of study

This is a multi-site, randomized, open-label, to compare the efficacy of aripiprazole augmentation, rTMS augmentation, and switching to venlafaxine XR as treatments for treatment-resistant depression.

Detailed description of study

Subjects will be randomized to one of three treatment arms: a) aripiprazole added to the current antidepressant, b) rTMS added to the current antidepressant, and c) switching to venlafaxine XR. All subjects will be followed for 8 weeks to examine the efficacy of the study treatments.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Depression, Major depression, Depression, depression
  • Age: Between 18 Years - 80 Years
  • Gender: All
Updated on 07 Jul 2023. Study ID: TX4803

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

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