Mapping the Human Chronobiome

Brief Description Of Study

• We will look for time of day changes in those infected with HIV compared to those who are not. Individuals infected with HIV have changes in their biological rhythms, such as sleep problems, different levels of hormones, and a shift in blood pressure. Therefore, we wish to study the relationship between daily rhythms and HIV infection.

Clinical Study Identifier: TX4800

Detailed Study Description

We are looking to enroll 3 different groups: 1: Diagnosis of HIV infection with CD4+ counts <500 cells/mm3 while untreated; 2: Diagnosis of HIV infection with CD4+ counts <300 cells/mm3 on ARV; 3: Volunteers must be in good health as based on medical history, physical examination, vital signs, and laboratory tests as deemed by PI; • Volunteers are capable of giving informed consent; • Own a smartphone which installs the remote sensing applications; • Non-smoking; Male or Non-Pregnant & Non-breast feeding females

Additional Information About The Study

Your participation will take 16-18 weeks. You will receive $550 for completing the study. There are 10 Visits to The Center for Human Phenomic Science, (CHPS) at the Hospital of University of Pennsylvania. One 48 Hour session will take place at Visit 5 at 2pm through Visit 7. Biosample collections will take place every 6 hours till approximately 10 am. Conatct: LaVenia Banas E-mail:

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To: Research Study Investigator
Subject: I am interested in participating in your Research Study
Dear Investigator,
I'm interested in learning more about and participating in your research study named: Mapping the Human Chronobiome
I am hoping to hear back from you and discuss details of the study

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