Vcrc Longitudinal Protocol For Granulomatosis With Polyangiitis (Wegener’S) And Microscopic Polyangiitis: 5505

Brief Description Of Study

The study is being done to learn more about Granulomatosis with Polyangiitis (Wegener’s) (GPA) and Microscopic Polyangiitis (MPA). These diseases affect the small and medium sized blood vessels in your body. The purpose of this study is to discover new biological markers (biomarkers) in patients with GPA or MPA that will: a) measure the amount of active disease occurring at any given time b) predict what types of problems patients are at risk for in order to help choose the best treatment c) predict whether patients will respond to specific treatments We will collect clinical information, information from research questionnaires, and blood and urine samples. Patients will be in the study for 15 years. We are not studying any new or experimental treatments.

Detailed Study Description

Clinical information and blood and urine specimens will be collected at your usual clinic visits. The types of information collected will include medical history details, medication use, physical exam findings, results of laboratory and diagnostic imaging tests (x-rays, MRIs, PET scans). Blood and urine specimens will be collected and sent to research laboratories that are looking to discover proteins, genes, and other chemicals that could serve as new biomarkers. Biomarkers are molecules that that can be used to measure biological processes in the body. This study is a project of the Vasculitis Clinical Research Consortium (VCRC), which is a consortium of investigators in major North American vasculitis centers. The VCRC is funded through the National Institutes of Health as a Rare Diseases Clinical Research Network with the purpose of promoting research in vasculitis.

Clinical Study Identifier: 00315393

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To: Research Study Investigator
Subject: I am interested in participating in your Research Study
Dear Investigator,
I'm interested in learning more about and participating in your research study named: VCRC Longitudinal Protocol for Granulomatosis with Polyangiitis (Wegener’s) and Microscopic Polyangiitis: 5505
I am hoping to hear back from you and discuss details of the study

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