Investigational Drug Study for Partial Seizures (YKP3089)

Site Image

Study Overview

This research study is designed to evaluate the safety of an investigational drug called YKP3089 and to help researchers understand how YKP3089 and other anti-epileptic drugs affect each other in the body when taken together.

Study Description

We are looking for patients with partial epilepsy who have uncontrolled or poorly controlled seizures despite having been treated with other anti-epileptic drugs. If you are eligible and decide to participate, you will be asked to come to Penn for outpatient visits that will last about 1-2 hours. At first, you will start taking small amounts of YKP3089 and gradually increase the dose under the study doctor's supervision, which is known as titration. Visits during the titration phase will be every 2 weeks. Then, once the desired dose is reached, you will need to come in less often. This is called the maintenance phase. Study visits may include the following procedures: vital signs, blood draw, physical and neurological exams, and questionnaires. You will not be asked to stop any other medications you may be taking.

Additional Information:

You will receive a $50.00 reimbursement per completed study visit, which totals $750 if you complete all study visits 1-15. If you choose to remain in the study past one year, you will receive $50.00 for each study visit that you attend. If you leave the study early, you will receive an amount based on the visits that you have completed. We can also help pay for transportation to and from Penn if needed.

  • Study Identifier: 820244

Recruitment Status

Enrolling By Invitation

If you need assistance finding a non-cancer study or if you have any questions, please email

Volunteer Sign up

Volunteer Sign-up

Participate in medical studies to develop new diagnostic and clinical treatments and improve current standards of care.

Sign Up Now!

If you need assistance finding a non-cancer study or if you have any questions, please email