VCRC Longitudinal Protocol for Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss): 5506

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Study Overview

The study is being done to learn more about Eosinophilic Granulomatosis with Polyangiitis (EGPA), also known as a Churg-Strauss, a disease that affects the medium and small blood vessels in the body. The purpose of this study is to discover new biological markers (biomarkers) in patients with EGPA that will: a) measure the amount of active disease occurring at any given time b) predict what types of problems patients are at risk for in order to help choose the best treatment c) predict whether patients will respond to specific treatments We will collect clinical information, information from research questionnaires, and blood and urine samples. Patients will be in the study for 15 years. We are not studying any new or experimental treatments.

Study Description

Clinical information and blood and urine specimens will be collected at your usual clinic visits. The types of information collected will include medical history details, medication use, physical exam findings, results of laboratory and diagnostic imaging tests (x-rays, MRIs, PET scans). Blood and urine specimens will be collected and sent to research laboratories that are looking to discover proteins, genes, and other chemicals that could serve as new biomarkers. Biomarkers are molecules that that can be used to measure biological processes in the body. This study is a project of the Vasculitis Clinical Research Consortium (VCRC), which is a consortium of investigators in major North American vasculitis centers. The VCRC is funded through the National Institutes of Health as a Rare Diseases Clinical Research Network with the purpose of promoting research in vasculitis.

  • Study Identifier: 816113

Recruitment Status


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