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Found 1070 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Open-Label Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients With Parkinson's Disease

A Open-Label Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients With Parkinson's Disease

35-80 years
All genders
Phase 1
Interventional
This is a 5 year study and the purpose is to assess the safety and tolerability of 2 dose levels of PR001A administered via l injection in patients with moderate to severe Parkinson's Disease
 Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)

Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)

18-65 years
All genders
Interventional
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation using human leukocyte antigen-mismatched unrelated donors for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children.
 Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

12-99 years
All genders
Phase 3
Interventional
The purpose of this superiority study is to evaluate the efficacy and safety of exebacase in addition to standard of care antibiotics (SoCA) compared with SoCA alone for the treatment of patients with Staphylococcus aureus (S. aureus) bloodstream infections (BSI), including right-sided infective endocarditis (IE). Patients will be randomized to …
 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

18-39 years
All genders
Phase 3
Interventional
The first purpose of this study is to test the safety of the addition of a drug called inotuzumab to the usual chemotherapy drugs used for adolescent young adults (ages 18-39). Inotuzumab is investigational and is not FDA-approved. Additionally,this study is to compare any good and bad effects of using …
 Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

18-65 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety and tolerability of a combination of the broadly neutralizing antibodies (bNAbs) GS-5423 and GS-2872 in combination with the HIV capsid inhibitor lenacapavir (LEN).
 A study to assess the safety and tolerability of nebulized PC945 for prophylaxis or pre-emptive therapy against pulmonary aspergillosis in lung transplant recipients.

A study to assess the safety and tolerability of nebulized PC945 for prophylaxis or pre-emptive therapy against pulmonary aspergillosis in lung transplant recipients.

18-99 years
All genders
Phase 2
Interventional
The purpose of this study is to learn about how safe and effective a new investigational drug, PC945, can be. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA). PC945 is an inhaled drug being studied for the prevention of a …
 Personalized Atrial Fibrillation Ablation with Ablation Index Adapted to Left Atrial Wall Thickness: The Ablate-by-LAW Pilot Study

Personalized Atrial Fibrillation Ablation with Ablation Index Adapted to Left Atrial Wall Thickness: The Ablate-by-LAW Pilot Study

18-99 years
All genders
Interventional
This study will use ADAS 3D LA™ software modules on your cardiac computed tomography angiography (CTA) to analyze Left Atrial Wall Thickness (LAWT) and the distance from the LA to the Esophagus (LA DIST). A CTA is a noninvasive test used to focus on coronary arteries. It allows doctors to …
 The Gen-Y Study: Randomized trial of universal vs. guideline-directed germline testing among young adults with cancer

The Gen-Y Study: Randomized trial of universal vs. guideline-directed germline testing among young adults with cancer

18-40 years
All genders
Our study aims to determine whether genetic testing should be recommended for young adults with cancer. This type of testing can show if your cancer may be caused by inherited risk.  This information can help guide effective screening and treatment for cancer in young adults and their families. This is …
 General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

18-64 years
All genders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
 General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

18-75 years
Healthy Volunteer
All genders
The goal is to conduct a screening procedure to be used in evaluating individuals either with or without an alcohol use disorder (AUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, genetic study, or other research protocol that matches their …
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