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Found 24 pulmonary-allergy-and-critical-care trials

A listing of pulmonary-allergy-and-critical-care medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Effect of study drug IL-4RR576 polymorphism on response to dupilumab in asthma

Effect of study drug IL-4RR576 polymorphism on response to dupilumab in asthma

18-99 years
All genders
Phase 4
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …

Semaglutide for weight loss in advanced interstitial lung disease: A Pilot Study

18-99 years
All genders
The aim of the pilot study is to demonstrate feasibility and tolerability of semaglutide in patients with obesity and advanced ILD. 
 ARISE - Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)

ARISE - Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)

18-99 years
All genders
Phase 3
The purpose is to validate patient-reported outcomes questionnaire subjects given ALIS (amikacin liposome inhalation suspension) as part of a study treatment regimen for NontuberculousMycobacterial (NTM) Lung Infection. It will also evaluate the safety and efficacy of the study treatments with ALIS, azithromycin, and ethambutol. Targeted population is patients newly diagnosed …
 ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)

ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)

18-99 years
All genders
Phase 3
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms in subjects newly diagnosed with NTM lung infection caused by MAC who have not started standard treatment. This is an experimental clinical research study, and ALIS is …

STOP360

99 years and younger
All genders
This study is trying to answer the following questions about treating a pulmonary exacerbation: Do participants have the same improvement in lung function and symptoms if they are treated with one type of antibiotic (called beta-lactams or -lactams) versus taking two different types of antibiotics (tobramycin and -lactams)? Is taking …

AP-PA02-201

99 years and younger
All genders
This study is for patients who have NCFBE who also have comorbid P aeruginosa infections. This study is testing AP-PA02 as a possible treatment for these infections and consists of 5 phages. The study includes physicals, infectious disease blood tests, ECGs, HRCT, blood and urine safety labs and phage labs …

VIGOR

99 years and younger
All genders
Prospective, single arm, non-randomized, open label trial evaluating the pathologic response of soft tissue ablated with pulse electric fields in patients with non-small cell lung cancer (NSCLC) who may be candidates for resection following standard of care neoadjuvant use of checkpoint inhibitor treatment plus platinum doublet chemotherapy.

IMPAHCT:

99 years and younger
All genders
This phase 2b/3 study will use AV-101 dry powder for oral inhalation in patients with PAH. Procedures include PEs, vital signs, safety labs, right heart caths, echocardiograms, QOL questionnaires, 6MWTs, lung function tests, and PK labs.

EFC17801

99 years and younger
All genders
The study will investigate the eficacy and safety of belumosudil compared with placebo, administered on top of azithromycin and SOC regimen of immunosuppression in male or female participants at least 1 year after bilateral lung transplant, at least 18 years age and with progressive CLAD despite azithromycin.

INCB039110-801

99 years and younger
All genders
The purpose of this study is to provide continued treatment with itacitinib to participants who are currently enrolled in the Parent Study of itacitinib.
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