Found 44 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
APPRAISE Study- Assessment of Primary Prevention Patients Receiving An ICD
The value of Antitachycardia Pacing (ATP) in primary prevention patients who receive implantable cardioverter defibrilator (ICDs) is uncertain. The purpose of this study is to better understand the value of ATP in primary prevention patients. This study is to see if certain programing will reduce the number of shocks received …
Destination Therapy Post Approval Study Product Surveillance Registry Platform Addendum and Apogee
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
Studying symptomatic Transthyretin Amyloid Cardiomyopathy for those who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
Phase 3
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
REAL-AF Registry: Real-World Experience of Catheter Ablation for the Treatment of Symptomatic Paroxysmal and Persistent Atrial Fibrillation Using Novel Contact Force Technologies
The REAL AF Registry is an observational, prospective, non-randomized registry designed to find out more about the outcomes for patients who receive an ablation as treatment for Paroxysmal Atrial Fibrillation (PAF) and Persistent (PsAF) Atrial Fibrillation. The registry aims to better understand real-world information for patients with this disorder. Eligible …
INTEGRA-D: Assessment of the Safety and Efficacy of a Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Subjects With Heart Failure and Reduced Ejection Fraction
The OPTIMIZER® INTEGRA CCM-D System, also known as a “Cardiac Contractility Modulation – Defibrillator” is an investigational device system that combines CCM® therapy and ICD therapy into one device. CCM therapy has been shown to improve heart failure symptoms. This clinical trial is designed to determine if the OPTIMIZER® INTEGRA …
Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance
This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …
EMPACT-MI
Phase 3
This clinical trial is enrolling participants that have had a heart attack, (also called acute myocardial infarction or MI). Even though treatments have made progress, researchers are still trying to improve care for heart attack patients, who are at increased risk for heart failure and death. The purpose of this …
STRIDE Study : The Effects of semaglutide on functional capacity in pith type 2 diabetes and peripheral arterial disease
Phase 3
This is a 52 week, randomized, double-blind, placebo-controlled trial comparing semaglutide 1 mg versus placebo both added to standard of care and administered once weekly in subjects with Type 2 Diabetes Mellitus with Intermittent Claudication.
RESTART study
Interventional, prospective, single-arm, multicenter clinical investigation. The purpose of this study is to evaluate the additional benefit of targeting specific areas in the heart during a repeat ablation procedure using a new medical decision support software called VX1. Patients with documented atrial fibrillation recurrences who had previous ablation procedure for …
Farapulse Advent Study
This investigation is a prospective, randomized, multi-center IDE pivotal study comparing the FARAPULSE Pulsed Field Ablation System to standard of care RF and cryoballoon ablation in subjects with drug-resistant symptomatic PAF. Subjects with documented drug-resistant (Class I-IV) PAF who have had 2 PAF episodes within 12 months of enrollment will …
